The Connection Between Epilepsy, Bipolar Disorder, and Headaches: What You Need to Know
- vladasyn
- Mar 2
- 3 min read
Understanding the Link Between Epilepsy and Bipolar Disorder
Did you know that epilepsy and bipolar disorder (BD) are closely connected? Studies show that people with epilepsy are at a higher risk of developing bipolar disorder, and vice versa. The connection is due to shared brain mechanisms, including neurotransmitter imbalances, brain circuit dysfunction, and inflammation.
Why Do They Overlap?
✔️ Brain Hyperactivity: Both conditions involve excessive electrical activity in the brain, particularly in the temporal lobe (which controls emotions and memory).✔️ Genetics: If you have a family history of either condition, your risk for the other increases.✔️ Neurological Factors: Changes in brain chemistry and structure may contribute to both conditions.
Real-Life Example
Sarah’s Story: Sarah, a 28-year-old with temporal lobe epilepsy, had seizures for years before noticing extreme mood swings. At first, healthcare providers thought it was depression, but after a thorough evaluation, she was diagnosed with bipolar disorder type II. With the right treatment, she found relief from both her seizures and mood instability.
If you or a loved one experience both seizures and mood swings, talk to a healthcare provider about getting a referral to a neurologist and a mental health specialist. A combined approach can help manage both conditions effectively.
The Link Between Seizures and Headaches
Many epilepsy patients experience headaches before or after a seizure, and some even report migraines that trigger seizures—a phenomenon sometimes called migralepsy.
Types of Headaches in Epilepsy
🔹 Postictal Headaches: Occur after a seizure, lasting from minutes to hours.🔹 Preictal Headaches: Happen before a seizure and can serve as a warning sign (aura).🔹 Interictal Headaches: Occur between seizures, especially in chronic epilepsy.
Real-Life Example
Anna’s Story: Anna, a 25-year-old with epilepsy, started noticing severe migraines with flashing lights before her seizures. An evaluation confirmed she had epileptic activity following her migraines, proving the link between migraines and seizures.
If you have frequent headaches along with seizures, a neurologist can help determine if they are related and recommend the right management plan. Ask your healthcare provider for a neurology referral.
Symptoms of Temporal Lobe Epilepsy (TLE)
Since TLE is the most common type of epilepsy linked to mood disorders, it’s important to recognize its symptoms.
Warning Signs (Auras) Before a Seizure
Déjà vu or jamais vu (strange familiarity or unfamiliarity)
Sudden fear or euphoria
Strange smells (burning, rotten, metallic)
Stomach sensations (nausea, rising feeling in the chest)
Seizure Symptoms (Focal Impaired Awareness Seizures)
Blank stare or unresponsiveness
Lip smacking, chewing, or repetitive hand movements
Confusion and memory loss after the seizure
Post-Seizure Effects
Fatigue and sleepiness
Headaches and nausea
Mood swings or emotional distress
Real-Life Example
Mark’s Story: Mark, 30, had episodes of confusion and lip smacking, which healthcare providers initially thought were panic attacks. However, an evaluation confirmed temporal lobe epilepsy. With appropriate care, both his seizures and mood swings improved.
If you have symptoms of TLE, mood changes, or unexplained episodes of confusion, ask your healthcare provider for a referral to a neurologist for further evaluation.
Key Takeaways
✔️ Epilepsy and bipolar disorder share brain mechanisms and often coexist.✔️ Seizures and headaches (especially migraines) are closely linked.✔️ Temporal Lobe Epilepsy can cause mood changes, memory issues, and personality shifts.✔️ Specialists in neurology and mental health can help manage these conditions together.
If you or a loved one experience seizures, mood swings, or frequent headaches, don’t wait. Talk to a healthcare provider about getting a referral to a neurologist and a mental health specialist.

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